Yohimbine HCL – Science of Burning Stubborn Fat

The supplement world these days never ceases to amaze me. There is always new and revolutionary research on both old and newly-discovered ingredients. One ingredient that has really picked up some momentum in recent years is Yohimbine HCL. The supporting evidence that this ingredient works very well as a mood/energy enhancer and more IMPORTANTLY a fat loss agent, continues to add up as more and more studies are done. So, how does it work? Where does it come from? Where can I find it? All good questions which we will review in today’s write-up!

Like most supplements and ingredients, Yohimbine HCL is a derivative of a plant. In this case the bark of the Yohimbe tree. Yohimbine is the active alkaloid in the bark and it is extracted and processed into Yohimbine HCL. Modern medicine took a page out of ancient medicine with this one, as Yohimbine has been used for thousands of years, proving time and time again its effective medicinal use.

Yohimbine HCL is a mild MAO inhibitor (we covered MAO Inhibitors in our article on Hordenine HCL, be sure to check that out as well!), which will help give you a bump in energy and mood. As we progress through a diet and execute fat burning cardiovascular exercise, we will begin to feel run down both physically and mentally. Yohimbine HCL will aid in controlling the destruction of our “feel good” hormones and aminos, resulting in a more positive experience through these taxing activities.

The biggest benefit, and in my opinion most interesting effect, Yohimbine HCL plays is its roll in fat loss by inhibiting a regulatory process in fat cells, specifically in “stubborn fat areas”. In these stubborn fat areas (brown fat) we have a significant amount more alpha-2 (α2) receptor sites. These receptor sites do an annoyingly good job at preventing the fat cells from releasing their stores to be used as energy (process also known as “burning fat”). Yohimbine HCL is an alpha-2 antagonist, meaning it will combat this stubborn effect.

(*Brief interjection, without getting too far into the weeds, insulin utilizes the same receptor sites as Yohimbine HCL. This means, Yohimbine HCL is best used for fat loss, DURING a fasted state…..insulin levels are at their lowest at this time*)

Knowing the aforementioned, products that contain Yohimbine HCL are great tools to incorporate in with your fasted cardio. So as your body turns to its fat stores for energy during this level of activity, Yohimbine HCL will be efficiently working in your system to “break up” the brown fat to be used as an energy source!

Yohimbine HCL and a stimulant, such as caffeine, work synergistically together bringing you the most efficient results possible. A lot of companies see this POWERFUL duo, and incorporate BOTH into their fat burning products. I personally use and recommend to my clients Chrome Supps Blaze Intense 3G for this exact reason. Follow the dosing instructions on the bottle and incorporate it into your fasted cardio sessions to Blaze through stubborn fat areas!


“Yohimbine: the effects on body composition and exercise performance in soccer players.” Ostojic SM

Res Sports Med. PubMed Oct-Dec 2006. Journal. 24 Oct 2016.

Indexed for Medline


“Yohimbe – herb of controversy and potential.” Chinese Herbs. 21 Oct. 2014. Web. 26 Oct. 2016